The acute fatty liver (AFLP) of pregnancy is an obstetric emergency, which leads to high maternal and fetal sickness and mortality. This is a relatively rare but severe complication of pregnancy with 5 cases of pregnancy per 1 million pregnancies. In their third trimester, women may experience this condition due to excessive fat statements in liver parenchyma and acute liver dysfunction.

While the exact cause is not known, experts tell us that it may be associated with mitochondrial dysfunction and genetic factors. “It is associated with a hereditary enzyme deficiency, usually a long-chain 3-hydroxesill-COA dehydrogenase (LCAD), resulting in a spoiled fatty acid metabolism in the liver,” Dr. Vidyashree Kamath, KMC Hospital, Dr. Bribeder Circle, Mangalore says.

Neither a prevention, nor an estimated complexity, initial diagnosis and treatment can prevent life-drew complications from acute fatty liver during pregnancy.

In the last quarter, a pregnant woman may experience nausea, vomiting, fatigue, loss of appetite or even jaundice. Dr. According to Sparthi Ji Jenny, Manipal Hospital, Whitefield,

He can also have an upper abdominal pain, which is unusual and stable.

Dr. Excessive thirst can be another important symptom, says Kamath. The progressive form, she says, can be more severe and can turn into the right upper abdominal pain, jaundice, confusion and consciousness, when severe.

“AFLP is more common in disabled women, women carrying twins or male embryos, low body mass index (BMI), or women who have diabetes, pre -praympasia, or intrahepatic cholestasis, are in the diagnosis of pregnancy, which are caused by these associations, caused by these associations.

What about diagnosis?

Dr. According to Jenny, the diagnosis is mainly based on clinical symptoms and some blood tests including liver function tests, coagulation profiles, sugar testing and abdominal and pelvic ultrasound to find any evidence of liver and kidney damage. Dr. “A liver biopsy is required and usually occur only in cases that are unusual or uncertain,” says Kamath.

Fixed treatment remains as soon as possible, as it will relieve the liver from more damage and assist in recovery of the mother’s clinical status. “After delivery, the liver function usually takes about 10 days to normalize,” Dr. Jenny says.

Dr. Kamath says that management involves rapid distribution of foats – usually through the Caesarean section – after stabilizing the mother. According to him, this is the only effective treatment, and it creates rapid improvement because once the placenta is removed, the progression of the disease stops. She says, “The risk of the organ, cogulopathy and the risk of sepsis require auxiliary care in high-level feature.

In addition, with quick treatment, most mothers perfectly recover from this condition after 7-10 days. Thanks to maternal mortality, better recognition and treatment, now has reduced to 5%. Timely diagnosis and treatment are still important for the mother and child to improve the diagnosis of the disease.

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