There has been a worrying rise in end-stage renal disease or ESRD among young adults above 25 years of age in India – raising concerns among doctors. Experts say the sharp rise in the condition among youth, coupled with high rates of kidney disease in the older population, underscores the urgent need for awareness, prevention efforts and organ donation initiatives.

In ESRD, also known as kidney failure – there is a gradual decline in kidney function that progresses to an advanced stage. Your kidneys filter wastes and extra fluids from your blood and stop working to meet your body’s needs. Then, they lose their ability to filter, causing dangerous levels of fluids, electrolytes and waste to accumulate in your body.

“Modern lifestyle, including poor dietary habits and physical inactivity, is an important driver. The increasing consumption of processed foods rich in unhealthy fats, oils, salt and sugar contributes to obesity, type 2 diabetes and high blood pressure – the three most common causes of kidney disease globally,” Dr Saurabh Pokhriyal, co- -Founder and Director, Vituscare Medlife Pvt. Ltd told Times Now.

Dr Pokhriyal said sedentary work and lack of regular physical activity also aggravate the conditions – which can only be controlled by dialysis or kidney transplant to ensure survival. Additionally, environmental factors such as exposure to heavy metals in drinking water and widespread use of pesticides in food production can lead to kidney inflammation and damage. “Indiscriminate use of over-the-counter analgesics and antibiotics also poses risks, as these drugs can have harmful effects on kidney function if used without proper medical supervision,” he said.

What are the genetic predispositions that lead to this condition?

According to experts, genetic predisposition also plays an important role in the development of ESRD, as some inherited conditions can directly affect kidney function. Polycystic kidney disease (PKD) is one of the most common genetic disorders leading to ESRD, where fluid-filled cysts develop in the kidneys, which gradually impair their ability to filter waste. “This condition often progresses over time, with symptoms becoming noticeable only in the later stages, making early diagnosis difficult,” said Dr Mayank Lodha Seth, chief pathologist at Radcliffe Labs.

According to Dr. Seth, gene mutations control blood pressure and those with a family history of high blood pressure are more likely to inherit traits that cause high blood pressure, a major risk factor for kidney disease. Is. “Over time, uncontrolled high blood pressure damages the blood vessels in the kidneys, leading to ESRD,” he said.

How can you prevent ESRD?,

To prevent ESRD, Dr. Pokhriyal says a multifaceted approach is needed that focuses on both lifestyle modifications and medical awareness. “Adopting a balanced diet low in processed foods, salt and animal protein along with regular physical activity can help reduce the risk of developing diabetes and high blood pressure – major risk factors for kidney disease,” he said. He said.

In addition you also need:

• Maintain a healthy body weight
• avoid smoking
• avoid drinking alcohol
• Manage pre-existing conditions like diabetes and high blood pressure

Additionally, it is necessary to increase public awareness about the dangers of self-treatment with over-the-counter painkillers and antibiotics. Seeking timely medical advice for any health concerns and regularly monitoring kidney function can help in early detection and management of kidney disease before it progresses to ESRD.

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