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Canāt get rid of acne? Your protein supplements may be the culprit
Supplements such as whey protein, high-dose vitamins B6 and B12, and iodine-rich seaweed may cause acne in some people. Research suggests their role in increasing oil production and inflammation. Switching to a non-dairy protein powder and monitoring skin changes may help.

Canāt get rid of acne? Your protein supplements may be the culprit (Image credit: iStock)
Have you ever wondered if your acne is caused by more than just hormonal changes? Sometimes, the cause isnāt just puberty or stress, but also simple things like lifestyle habits or even dietary supplements. When we think of acne, hormonal changes, poor skin care routines or genetics often come to mind. However, several clinical cases and research have shown how certain supplements, including whey protein, vitamins, and even iodine-rich seaweed, can cause acne in some people. One example comes from a case published in the online journal Dermatology.
A 16-year-old boy developed severe acne that left his dermatologist shocked. Even after being given Accutane, a powerful acne medication, his condition did not improve. After revisiting the boyās medical history, the dermatologist discovered that he regularly consumed whey protein powder to build muscle. Once the boy switched to non-dairy alternatives, his acne improved significantly. This suggests that many people donāt realize that āall-naturalā supplements can sometimes have side effects, including triggering or worsening acne.
Common Supplements Linked to Acne
Several over-the-counter supplements have been linked to acne outbreaks. Hereās a look at the main culprits:
1. Whey Protein Powder
Whey protein derived from milk is a popular choice for building muscle. However, its high concentration of insulin-like growth factor 1 (IGF-1) can stimulate the sebaceous glands, leading to increased oil production and clogged pores.
2. Muscle Building Supplements
Some supplements in this category are contaminated with androgenic steroids, which are known to enlarge sebaceous glands and alter skin bacteria, both of which can cause acne.
3. High-Dose Vitamins B6 and B12
These vitamins, which are often taken to boost energy or correct deficiencies, have been linked to inflammatory acne eruptions, although the exact mechanism is still unclear.
4. Iodine-rich Seaweed Supplement
Seaweed supplements, especially those high in iodine, may aggravate acne by increasing inflammation and causing pus-filled bumps on the face and upper body.
Types of Acne Caused by Supplements
Acne can appear in different forms depending on the supplement and various skin reactions:
ā Comedonal acne: blackheads and whiteheads
ā Papular acne: red rash
ā Pustular acne: pus-filled pimples
ā Nodulocystic acne: large, painful cysts and nodules
In some cases, specific supplements may trigger a particular type of acne. For example, iodine obtained from seaweed supplements often causes pimples, while whey protein is more likely to cause nodulocystic acne.
Research Findings: Supplements and Acne
The medical literature has documented several cases and studies linking supplements to acne:
ā A study conducted on 30 men who took whey protein supplements for 30 days showed a significant increase in acne lesions, including pustules and comedones.
ā Several cases involving male bodybuilders and teenagers showed significant improvement in acne after discontinuing whey protein.
ā High-dose vitamin B12 has been included in cases where patients develop facial acne after injection or oral supplementation.
Why do these supplements cause acne?
1. Whey Protein
Whey protein contains high levels of IGF-1, which can increase oil production and clog pores. Concentrated whey supplements are particularly potent, sometimes equivalent to the protein content of 6-12 liters of milk.
2. Muscle Building Supplements
These often contain androgenic steroids, either intentionally or through contamination. Steroids enlarge sebaceous glands, increase oil production, and alter skin bacteria, creating a perfect storm for acne.
3. Vitamin B6 and B12
Although the exact cause is unclear, high doses of these vitamins are known to cause inflammatory acne, especially on the face, neck, and back.
4. Iodine
The high iodine levels in seaweed supplements can irritate the skin and increase acne, especially in areas such as the shoulders, back, and face.
Which protein powders are safe?
For those prone to acne, switching to an alternative protein powder may help reduce the risk. Options include:
ā Pea Protein
ā egg protein
ā Hemp Protein
ā Mixed Plant Protein
ā Brown Rice Protein
These options are not usually associated with acne. However, it is essential to choose high quality products that are free from contamination.
What should you do if supplements cause acne?
If you suspect a supplement is causing your acne:
1. Stop the supplement
Acne often resolves slowly after discontinuing the harmful product. However, consult your doctor before stopping any prescribed supplement.
2. Monitor skin changes
Track your skinās reaction for a few weeks to confirm whether the supplement was the cause.
3. Choose option
Opt for non-dairy protein powder or lower doses of vitamins if necessary.
4. Maintain a skin care routine
Proper skin care can help manage acne symptoms during this infection.
Acne caused by supplements is more common than many people realize. From whey protein to high-dose vitamins, these products can have a significant impact on your skin, especially if youāre prone to acne. Therefore, it is essential to understand the relationship between supplements and acne which can help you make informed choices to protect the health of your skin. Always consult a dermatologist or health expert if you think your supplements are affecting your skin, as small changes in lifestyle can make a big difference.
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