A recent study found that young women using progesterone-keval form of birth control pills may have a high risk of asthma attacks. Research published on May 7 in ERJ Open Research, highlights a possible health concern for women under 35 that opt ​​for this contraceptive method.

Dr. Dr, a clinical senior lecturer in respiratory epidemiology at Imperial College London. Powered by a team of researchers led by Cloe Bloom, the study examined the health data of about 262,000 women between the ages of 18 to 50 in the United Kingdom, all of which were detected asthma. The study extended from 2004 to 2020.

Researchers compared the results of asthma among women who had never used a contraceptive pill and began using the combined estrogen-procesterone pellet or progesterone-keval version. Their findings indicated a significant link amidst an increased incident of progesterone-cables and an increased incident of asthma attacks in women under 35 years of age.

In particular, these women experienced 39 percent higher risk of asthma attacks, if they were using progesterone-keval pill. In contrast, no increased risk was observed in the joint pellet users. “We found that the joint bullet did not affect whether women had asthma attacks, but some women who took the progesterone-only bullet, there were more asthma attacks,” Dr. Bloom said.

This increased risk was particularly noticeable among women who were taking less asthma drugs, such as a breath corticosteroid or oral steroids, and high blood eosinophil levels – a marker of inflammation is often associated with more severe forms of asthma. For these groups, the Progesterone-Cowlle pill increased the risk of asthma attacks by 20 percent and 24 percent respectively.

Dr. Bloom insisted that asthma is a significant health concern among women, which is more likely to suffer from the condition, but also double the possibility of dying of asthma as men. He explained, “To help prevent these deaths, we need a better understanding of why women are at greater risk.”

The study suggests that excessive progesterone can contribute to an increase in inflammation in the airways. However, researchers also admitted that other unknown factor may make some women susceptible when using progesterone-cavalry contraception.

Dr. A respiratory medical specialist at the University Hospital, Epostolos Bosios, Karolinska, Stockholm and advisor to the European Respiratory Society, praised the study as a step in understanding gender-specific asthma risks. He advised women suffering from asthma to have an open discussion about contraceptive options and asthma management with their doctors.

“This study helps women and healthcare professionals make more informed decisions, which can be the best for them,” Dr. Bloom said.

As team continues to discover the role of sex hormones in respiratory health, future research may be investigated how pregnancy or hormone replacement therapy affects asthma in women.

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