The first person in the UK to have all of her major organs transplanted – a heart, liver, lungs and a kidney – has died aged 46 – more than a decade after her groundbreaking operation.

According to news reports, Allison Angell suffered from cystic fibrosisDue to which he had to undergo several major surgeries over a period of 11 years. Allison died in Dinas Powys, south Wales. She was awarded a Pride of Britain award in 2010 for her bravery in fighting her condition. The “national inspiration” also realized his longtime ambition to become a general practitioner in the same year.

Alison battled cystic fibrosis throughout her life

Allison was seven years old when she was told she was one of 10 percent of cystic fibrosis patients suffering from liver disease in the world. By the time she turned 17, Allison had a liver transplant and two years later was given a new heart and lungs.

Even though she could not complete her education in the subjects she wanted, Alison completed a neuroscience degree as a mature student before starting a degree in medicine. However, halfway through it was discovered that he had kidney failure. To save Allison’s life, her father David donated his kidney.

what is cystic fibrosis,

Cystic fibrosis is a genetic disease that causes sticky, thick mucus to accumulate in your organs, blocking and damaging them. While it mainly destroys your liver, it also affects your lungs and airways, making breathing difficult and causing frequent infections.

It also forms cysts and scarring or fibrosis in your pancreas, as well as blocks the ducts that release digestive enzymes, making it harder to get nutrients through your digestive tract. This condition also affects your liver, sinuses, intestines and sexual organs.

People who have this condition have reduced levels of certain proteins due to genetic mutations, or proteins that don’t work properly. Because of these faulty proteins, the water-carrying minerals in your mucus become trapped inside the cells, causing the mucus to become thick and sticky.

Cystic fibrosis is a congenital disease and is a lifelong disease that becomes more severe with time.

Cystic Fibrosis Signs and Symptoms

Some signs and symptoms of cystic fibrosis symptoms include:

• frequent lung infections
• loose or oily stools
• breathlessness
• frequent wheezing
• having frequent sinuses
• severe cough
• slow growth

What causes cystic fibrosis?

According to doctors, changes in CFTR The gene – also known as a variant mutation – that causes cystic fibrosis makes a protein that works as an ion channel on the cell surface. Ion channels are like gates in the cell membrane that allow certain molecules to pass through.

CFTR A gate is usually made for chloride ions, a type of mineral with a negative electrical charge. Chloride moves out of the cell, taking water with it, which thins the mucus and makes it more slippery. In people with this condition, the gene mutation occurs CFTR Prevent this from happening, so that the mucus remains sticky and thick.

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