Can change in cholesterol levels increase the risk of dementia? The study says yes

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Can change in cholesterol levels increase the risk of dementia? The study says yes

A new study suggests that elements with ups and downs in cholesterol levels face 60 percent more risk of dementia and increase the risk of 23 percent mild cognitive loss. Researchers suggest that monitoring cholesterol variability can help people identify at risk. Changes in lifestyle and maintaining stable cholesterol through medicine can reduce dementia risk.

Can changes in cholesterol levels affect brain aging? The study says yes (Image Credit: ISTOCK)

A new study shows that with seniors Cholesterol level Year -Dar -Sal can be at high risk of development of dementia significantly. Research published on 29 January in Neurology Journal found that people with the most variables Cholesterol There was a risk increased by 60 percent of dementia in levels compared to people with stable cholesterol. They were also 23 percent more likely to develop mild cognitive loss (MCI), an early sign of brain aging that can progress in dementia.

Cholesterol as a new dementia risk indicator

Fellow, a research from Mamat University in Melbourne, Australia. Zen Jhou said that cholesterol variability can serve as a biomarker to help identify those at risk of dementia. He said, “Cholesterol is measured, measured per year, can provide more information than reading a single cholesterol in determining dementia risk,” he said in a news release.

While high cholesterol at middle age is associated with prolonged cognitive decline, its role in brain health during old age is not clear. Some studies have suggested that low cholesterol may actually increase dementia risk, while others did not find any links.

How was the study done

To advance this, the researchers tracked over 9,800 seniors aged 65 years and above, who had no prior history of dementia or memory problems. His cholesterol level was measured at the beginning of the study and the beginning of three annual follow -up trips. The participants also conducted memory and cognitive tests every year.

After the third visit, researchers continued to monitor the participants for five years. During this period, 509 persons developed dementia.
Among people with ups and downs in the largest cholesterol, 147 out of 2,408 participants developed dementia-the rate of 11.3 per 1,000 person-year. In contrast, people with the most stable cholesterol levels developed only 98 out of 2,437 dementia, with a lower rate of 7.1 per 1,000 per year.

Role of ‘Bad’ LDL cholesterol

Researchers found that the increased risk, especially the ups and downs in the level of total cholesterol and LDL (poor) cholesterol, was linked. However, they found no significant connection between dementia risk and changes in HDL (Good) cholesterol or triglycerides.

Despite these findings, the study did not establish a reason-and-effect relationship between cholesterol changes and dementia. Instead, it only highlights a strong relationship between the two.

Why the rapidly rashes in cholesterol can affect the health of the brain

A potential explanation for this link is that unstable cholesterol levels can change fatty plates into the arteries, possibly leading to potential obstructions that reduce blood flow in the brain. This can increase the risk of mini-stroke or full-stroke, both known to cognitive decline.

Another principle is that cholesterol can be a symptom of underlying chronic diseases, such as diabetes or heart conditions, which may be real criminals behind dementia risk.

Cholesterol monitoring for better brain health

Dr. Zhou explains the importance of monitoring regular cholesterol in older adults. “Cholesterol of older people should be tracked over time to help identify the risk of cognitive loss,” he said. He also suggested that drugs such as lifestyle changes and statin can help maintain stable cholesterol levels and potentially reduce the risk of dementia.

While more research is required to confirm these findings, experts recommend that senior heart-healthy diet follow, exercise regularly, and existing health conditions to support both heart and brain health Manage
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