Hopefully ‘game-changing found’ can reduce chronic pain
Marlen Lowe has been with chronic pain for more than a decade, but believes that “ground-breaking discovery” by researchers can offer him and millions of fellow victims New Hope.
The 35-year-old Marlene, one of the five people in Scotland, is often seen as ineffective with standard pain relievers, with standard pain relievers.
Researchers at the University of Aberdeen have now said that they have found that chronic pain is physically different from other types of pain – which can help find the best way to treat it.
Marlene, who lives in Aberdeen, described the findings as “amazing”, as he said that it has recognized a disease that many people did not understand, and offered hope for the future.
The research team stated that they identified that chronic pain is processed differently in the nervous system by injury or pain.
He said that separate “physiological pathway” for this old type of pain means that it can now be a goal for future treatments.
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Marlene, who works in marketing, lives with his partner Mark and his Springer Spaniels Spocl and Paneer.
She says that her pain began in the early 20s when she started feeling ill “all the time” and what was wrong could not work.
“So I was getting sick for the next two years, my life was away from a way, and then I eventually came to know of chronic fatigue syndrome (CFS), which was a relief, but when you don’t even tell you that we can’t do anything about it, it’s not great,” he said.
“About five years ago, the pain was deteriorating, I got a new GP, and said ‘I need help’, and fibromialgia was diagnosed. Fibromyalgia is a neurological position that basically targets the nerve endings, so feel like a light brush (for hand).”
Speaking of day-to-day effects, Marlene said that she had to cut the tag of clothes as well.
“Even light brushes become like someone is stabbing me, repeatedly, repeatedly,” he said.
Marlein said that she takes antihistamines every day, not because she is a fever, but if she does not do it, her palms start to get itchy, and itching can then crawl her arms and make her body down.
“It really feels that you have found ants crawling under your skin,” she told the BBC Scotland News.
“You can scratch it, but after a few minutes it is back. Then there is muscle ache. If you can imagine when you really exercise, what it is, what happens, that just by cooking, or walking above the stairs.
“I have tried painkillers – and they have never worked.
“You start feeling invisible, because you don’t look like you are sick. You start mistrusting your body, and thinking that it should be in my head, which is mentally very harmful, as you are trying to live on top of life, work, relationships, and eating this pain continuously.”
He said that he had forced him to reconsider his plans for his life.
Senior Lecturer of Neurosciences at the University of Aberdeen. Gai Baywik said that not all pain can be treated in the same way, and the drug may be ineffective for chronic pain.
“Stating pain from sharp objects and surgery can usually be treated effectively with a common pain reliever, but chronic pain can not occur frequently,” he said.
“New remedies require a separate drug target. This study has found that goal.”
He said that the team found that a molecule called glutamate is released into the muscles to activate an unusual receptor.
They found that too much glutamate active pain release of veins, which make them permanently active, and they do not switch to them in general. Blocking the glutamate receptor can trigger chronic pain.
Dr. Baywik said: “This discovery means that scientists can now start developing new remedies that target this new pain passage which does not respond to standard painkillers.
“It has the ability to help many people whose pain is currently inadequate.”
What is chronic pain?
- Regardless of medicine or other forms of treatment, persistent pain lasts for more than three months
- Secondary chronic pain is a pain caused by another condition, for example, arthritis, endometriosis, cancer pain
- Primary chronic pain is a condition in itself – there is no known condition other than pain – it may include conditions such as fibromyalgia or complex regional pain syndrome
- Chronic pain is often confused with acute pain – a short -term pain such as a broken bone or torn muscle
Marlen hopes that research may one day “try to get through just 24 hours” no longer on repeating daily.
“I wanted to save the world, worked with animals, the orphanage, moving forward all the time,” she said. “But realizing that I can’t even manage a desk job without getting sick, in fact I have to mentally hit me. I have to fully evaluate how I live, how I am fit in the world.
“This is not the mind to talk, otherwise we will be able to fix it. It is so difficult to explain it to the people. I am choosing the option to live, I am not letting the pain win. For bad days, it is using a moving rod if I need. Mostly it is a sunlight.”
Can there be a pain-free future?
He said that research offered light at the end of the tunnel, as well as an understanding of the situation.
“I know nothing can be done right now to help the pain, and at the moment it is showing how they can prevent pain from being in the first place,” Marlen explained.
“The biggest thing is that it is valid. It is saying that the pain is there, it is present, you are not crazy. It’s fine if you do not understand the pain that is going through someone, but it is not right to dismiss it.”
He said: “I am happy to see that more work is being done to understand and try to treat the state of chronic pain.
“It expects me a pain-free future.”