Study finds painkillers may increase bleeding risk in people who use blood thinners

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Painkillers may increase the risk of bleeding in people who use blood thinners, study finds

A recent study published in the European Heart Journal found that people who use blood thinners had twice the risk of internal bleeding if they also took NSAIDs, commonly known as painkillers. There is risk. A new study suggests that NSAIDs may increase the risk of uncontrolled bleeding in the intestine, brain, lungs and bladder if taken with blood thinners. Read on to know more.

Painkillers may increase the risk of bleeding in people using blood thinners

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A new study found that people who use blood thinners If they also take non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen, which are commonly known to have double the risk of internal bleeding. pain relieverThis study was published in the European Heart Journal.
People are commonly given blood thinners to treat or prevent strokes, heart attacks or blood clots in the legs or lungs, the researchers said. On the other hand, NSAIDs are also known to thin the blood.
According to a US News report, a new study suggests that NSAIDs may increase the risk of uncontrolled bleeding in the intestine, brain, lungs and bladder if taken with blood thinners.
“We found that for patients taking blood thinners for blood clots in the legs or lungs, NSAIDs were less likely to cause blood clots than those not using NSAIDs,” said Soren Riis Petersen, a medical student and researcher at Aarhus University Hospital in Denmark. Using it doubles the risk of bleeding.
“The risk of bleeding associated with NSAID use was not limited to the digestive system, but also affected other organ systems.”
For the study, researchers analyzed data from nearly 52,000 Danish patients who received blood-thinning medication to treat blood clots between 2012 and 2022. In Denmark, the NSAIDs diclofenac and naproxen can only be obtained through a doctor’s prescription. This allowed researchers to track the health of patients who were prescribed both blood thinners and NSAIDs.
The researchers found that overall, when people took a blood thinner and an NSAID, the risk of bleeding was twice as high as when people took no blood thinners alone. The specific risk was four times higher for naproxen, three times higher for diclofenac, and almost twice higher for ibuprofen.
The study revealed specific bleeding risks including; There is a 2.2 times higher risk of bleeding from the intestine, 3.2 times higher risk of bleeding from the brain, 1.4 times higher risk of bleeding from the lungs, and 1.6 times higher risk of bleeding from the urinary tract.
The study also found that using NSAIDs with blood-thinning medications tripled a person’s risk of anemia.
The results showed that the pattern of risk remained similar across different types of blood-thinning drugs, including rivaroxaban, apixaban, dabigatran, edoxaban, and warfarin.
“For people who are taking blood-thinning medications for blood clots in their legs or lungs, our research suggests being cautious when considering NSAIDs for pain or inflammation,” Peterson concluded in a journal news release. Throws light on the importance.
“We recommend that patients consult their doctor before taking an NSAID with a blood thinner.”
“It appears clear that avoiding NSAIDs with (blood-thinning) medications is the safest strategy to avoid the risk of additional bleeding,” Dr. Robert Storey, professor of clinical cardiology at the University of Sheffield in the UK, said in an editorial. Is.
“However, if this is not possible, what mitigation can be done? NSAID prescriptions should obviously be at the lowest dose and for the shortest time possible, but the choice of agent and route may also be important.
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